Functional somatic syndrome: how it could be relevant to rheumatologists.

1: Mod Rheumatol. 2007;17(3):179-84. Epub 2007 Jun 20.

Masuko K, Nakamura H.

Department of Bioregulation and Proteomics, Institute of Medical Science, St. Marianna University School of Medicine, 2-16-1, Sugao, Miyamae-ku, Kawasaki, 216-8512, Japan, kmarianna@mac.com.

Functional somatic syndrome (FSS) is defined as a group of related syndromes characterized more by symptoms, suffering, and disability than by structural or functional abnormality. The diagnostic criteria and/or symptoms of FSS often overlap, and co-morbidity is commonly found among the diseases of FSS. For example, patients with irritable bowel syndrome often suffer from chronic pain, and a high percentage of co-morbidity can be found with fibromyalgia. Accumulating evidence indicates the presence of visceral and somatic hyperalgesia in FSS as a common feature, and the central sensitization mechanism has been suggested to play an important role in the pathophysiology of FSS. In the present article, the authors introduce the concept of FSS focusing on its possible relevance to rheumatology in terms of pain perception. A possible implication of mast cells and proteinase-activated receptor-2 (PAR-2) in FSS is also reviewed.

PMID: 17564771 [PubMed – in process]

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Folllowing Rick Usher's death in December 2008, at his request in September of that year, I had agreed, as his principal contributor and an experienced journalist, to run the FMS Global News service due to his heavy commitments to music and raising research funds through this avenue. Following his sad and sudden death I hope to continue his work as he would have wished.
This entry was posted in Arthritis, Article, Chronic Pain, Chronic Pain Disorders, Chronic Widespread Pain, Clinical Pain, Dysfunctional Pain Processing, Europe, Fatigue, Feeds, Fibrohugs, Fibrohugs News, Fibromyalgia, Fibromyalgia Blogs, Fibromyalgia News, Fibromyalgia News Belgium, Fibromyalgia News Deutschland, Fibromyalgia News France, Fibromyalgia News Israel, Fibromyalgia News Italy, Fibromyalgia News Japan, Fibromyalgia News Jerusalem, Fibromyalgia News Korea, Fibromyalgia News Southeast Asia, Fibromyalgia News Turkey, Fibromyalgia News Wisconsin, Fibromyalgia Press Releases, Fibromyalia News Germany, FMS, FMS Global News, FSS, Functional Somatic Syndrome, Global News, IBS, Invisible Illness, Invisible Illnesses, Irritable Bowel Syndrome, Japan, Medical Journals, Medical Research, Medical University, News, News Australia, News Belgium, News Canada, News France, News India, News Ireland, News Israel, News Italy, News Japan, News Jerusalem, News Korea, News Montreal, News Nigeria, News Norway, News Quebec, News Saskatchewan, News Scotland, News Southeast Asia, News Spain, News Sweden, News Toronto, News Turkey, News UK, News Wisconsin, Nigeria, North Carolina, Ontario, Osteoarthritis, Ottawa, Pain, Pain Management, Pain Matrix, Philadelphia, Rheumatism, Rheumatoid Arthritis, RSS, Seattle, Southeast Asia, Stockholm, Surrey and Sussex, Swedish, Syndromes, Tenderpoints, The Netherlands., Toronto, Universities, US, Virginia, Washington DC, World, World News. Bookmark the permalink.

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