Thermal and Visceral Hypersensitivity in Irritable Bowel Syndrome Patients With and Without Fibromyalgia.

Moshiree B, Price DD, Robinson ME, Gaible R, Nicholas Verne G.

1: Clin J Pain. 2007 May;23(4):323-330.

Departments of *Medicine daggerOral and Maxillofacial Surgery double daggerNeuroscience section signClinical and Health Psychology, University of Florida Colleges of Medicine, Dentistry, Public Health and Health Professions, Gainesville, FL parallelNorth Florida/South Georgia Veteran Health System.

BACKGROUND: Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder characterized by both visceral and somatic hyperalgesia, producing a similar effect seen with the central hypersensitivity mechanism in fibromyalgia (FM).

OBJECTIVES: The aim of the current study was to compare magnitudes of visceral and thermal hypersensitivity in IBS patients and FM patients with IBS (FM+IBS) compared with healthy controls.

METHODS: Female patients with IBS (n=12), FM+IBS (n=12), and control participants (n=13) rated pain intensity to hot water immersion (45 and 47 degrees C) of the hand/foot and to phasic distension of the rectum (35, 55 mm Hg) on a Mechanical Visual Analog Scale. The data were analyzed with 3 separate 1-way analyses of variance with post hoc Tukey tests.

RESULTS: For both thermal and visceral stimuli, the control group had lower pain ratings than either the IBS or FM+IBS groups.

PMID: 17449993 [PubMed – as supplied by publisher]

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Folllowing Rick Usher's death in December 2008, at his request in September of that year, I had agreed, as his principal contributor and an experienced journalist, to run the FMS Global News service due to his heavy commitments to music and raising research funds through this avenue. Following his sad and sudden death I hope to continue his work as he would have wished.
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One Response to Thermal and Visceral Hypersensitivity in Irritable Bowel Syndrome Patients With and Without Fibromyalgia.

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