Category Archives: PFMS

EUROPEAN NETWORK of FIBROMYALGIA ASSOCIATIONS

From the News Desk of Jeanne Hambleton

PRESS RELEASE -28.01.2009

 

The European Medicines Agency (EMEA) are to  have a consultation with a delegation from the European Network of Fibromyalgia Associations (ENFA) in an attempt to understand the need for medical treatments for fibromyalgia in Europe.


Brussels –
Following an invitation by the EMEA, the European Network of Fibromyalgia Associations (ENFA) has agreed to attend a consultation meeting with EMEA, where ENFA representatives will share their knowledge and experiences related to the disease of Fibromyalgia that some 14 million Europeans are suffering from.  One of the biggest challenges that the patients have been facing is the lack of officially recognized medical treatment options in the European Union whereas there are three drugs in the United States of America approved by the Food and Drug Administration: Cymbalta from Eli Lilly, Lyrica from Pfizer and recently authorised Savella from Forest & Cypress.

 

The European Declaration 69/2008 on Fibromyalgia that has been recently adopted by the European Parliament, symbolizing the awareness raised around Fibromyalgia, calls for actions on specific issues from European Institutions to improve healthcare surrounding the disease, e.g. investment in research and provision of better diagnosis and treatment.  In addition, the European Health Commissioner Ms. Vassiliou’s remarks (E-6262/08EN) on the treatment of Fibromyalgia demonstrates encouraging willingness of the European Commission to address various concerns laid out in the Declaration on Fibromyalgia.

“We hope that this new drive on Fibromyalgia awareness will bring the end to the impasse of medical treatment for Fibromyalgia patients in the EU”, said Mr. Robert Boelhouwer, President of ENFA. 

Fibromyalgia is a complex disease with a variety of symptoms in addition to the defining symptom – chronic widespread pain. It is estimated that 14 million people in Europe suffer from fibromyalgia and the condition is more prevalent with women (87%).  Fibromyalgia imposes large economic burdens on society as well as on affected individuals. The debilitating symptoms often result in lost work days, lost income and disability payments. Due to lack of awareness, on average patients in Europe see 3-4 physicians and take multiple medications over the course of several years before they receive a diagnosis of Fibromyalgia.

Mr. Boelhouwer said, “Increasing awareness of Fibromyalgia among healthcare professionals and patients will bring enormous benefits to patients, healthcare providers and the society in general by managing the burden of the disease.” he continues, “Having this in mind, ENFA welcomes the proactive role that both the European Parliament and the European Commission have taken up in raising the awareness of Fibromyalgia.”

 

 

Contact:  European Network of Fibromyalgia Associations (ENFA)

Mr. Robert Boelhouwer President of ENFA

contact@enfa-europe.eu  - www.enfa-europe.eu


 About ENFA

ENFA is a network of patient association and support groups working in close consultation with the national association in the relevant country. Our joint missions are to conquer the myths and misunderstandings around Fibromyalgia. The network will help collectively push forward the boundaries which currently exist in understanding, experiencing and treatment of Fibromyalgia. Our main goal is to see fibromyalgia receiving the recognition it deserves across Europe as an illness in its own right.


 

 

Fibromyalgia and Chronic Fatigue Self-Help Group Meeting

FOR IMMEDIATE PRESS RELEASE

Thursday, June 12th, 2008

The FIBROMYALGIA and CHRONIC FATIGUE SELF-HELP GROUP will meet Thursday, June12th, 2008 at 6:30 PM

at the Quest-4-Life Wellness Center, located at Lenoir Mall, Lenoir, N . C.

Denise Lindsay, BS, LMBT of Wellspring Therapeutic Massage Care will present the program. She will include a demonstration of her own “Gentle Massage Technique for Fibromyalgia” and will also offer the group sample sessions free of charge. There will be no meeting July and August.

For more info, call Nancy at 828-758-2156 or Lindy at 828-754-2064.

FMS Global News

Fibrohugs Support

Tenderpoints Newsletter

Musicians Supporting Research

CONGO’S BILL AND THE RACE AGAINST TIME

by Jeanne Hambleton  © 2008
NFA Leader Against Pain-Advocate  

A committee of the New Jersey Senate has considered a new bill called Congo’s Law and there are hopes that Congo, the German Shepherd dog, will no longer be under sentence of death.

See original story: Congo gets world wide support

Congo was put on “death row” last June as a vicious dog after protecting his mistress, a female dog and three puppies, from an alleged attack with rake by a gardening contractor. When news of her fate reached the Internet animal activists and dog lovers all over the world signed petitions and sent emails to the Judge in Princeton, home of Congo, to save the dog’s life.

This week thanks to a friend, Anne Soden, who lives in Princeton and took part in one of the demonstrations to save Congo, I can bring you news that an American Assemblyman called Neil M Cohen from the New Jersey Senate has proposed a Bill to save the life of Congo, the German Shepherd dog sentenced to death. Thanks Anne.

Neil Cohen is quoted as saying,”Congo’s case underscores the need for the state to modernize the law that deals with dog attacks so it is fair for the owners and the animals.”

Congo’s Bill would revise state animal control law provisions that are alleged to be archaic and barbaric, by making it more difficult to label a dog vicious or to put an animal down.

But a USA website (http://abbyK9.blogspot.com) which shows a picture of two of the James children with Congo, adds a cautious note to say, “Please note that Congo being returned to his family is only temporary while the case goes through the appeal. Congo could still be put to sleep for protecting her family. So please, keep contacting the governor’s office to have this matter put to rest once and for all. The calls and emails are helping!” Details of who and where to write or email appear later in this story.

NEW JERSEY SENATE

In December Congo’s Bill, that would immediately change the state’s vicious dog laws, made its first passage through the Senate.

The New Jersey Assemblyman Neil Cohen, who took this action, is an avid defender of the rights of animals and has sponsored several measures to ensure the humane treatment of animals. He has met Congo and his owners, the James family, at their home in Princeton to raise awareness of his legislation and the dog’s potential fate. Neil Cohen says that under current law the only defense for a dog declared vicious is if the dog has been provoked and acted in defense to protect itself, its offspring, its owner or a family member of the owner.

“The nature of a dog is to protect those around them,” said the Assemblyman. “It’s outrageous that Congo may have been provoked into attacking and this fact is being ignored by authorities.”

A lawyer for Congo’s owners has argued that Congo was provoked when the dog mauled a landscaper on June 5 outside a home in Princeton Township. Neil Cohen’s bill (A-4597) will clarify and revise the current vicious dog law to make it more equitable.

The bill would take into consideration provocation by treating a dog provoked to attack differently than an unprovoked dog that caused bodily injury to a person or domestic animal during an attack.

The Assemblyman said the bill would define striking, grabbing, poking and prodding as threatening actions and behaviors that could incite a dog to defend itself, its offspring or its owner or the owner’s family. The legislation would raise the bar for declaring a dog as vicious. It would require a dog to be found vicious beyond a reasonable doubt — the same standard used for humans charged with a crime. The measure also would give municipal courts an alternative to humanely destroying a vicious dog by giving the owner the option to comply with precautions for keeping a potentially dangerous dog.

During the disposition and appeals process, the bill would allow an owner to keep their dog as long as they complied with current law’s precautions for keeping a potentially dangerous dog. Precautions for owners keeping a dog deemed potentially dangerous include posting signs on their property and minimizing a dog’s potential threat to people and other animals. The bill also would allow an owner and owner’s family to visit their dog during times when their dog might be impounded. The bill would establish a three-month statute of limitations for animal control officer to seize and impound alleged vicious or potentially dangerous dogs.

Neil Cohen said the vicious dog law has not been amended since 1994 and it is long overdue for an update. He hoped his legislation would be fast tracked into law to save the life of Congo.

Congo was ruled vicious by Princeton Township Municipal Judge Russell Annich, Jr., who also ordered that the dog be put down. The judge’s decision has since been stayed and a state Superior Court Judge has allowed the dog to return to his home, pending appeal, with numerous restrictions, including that he is muzzled and kept in a fenced area.

The fate of Congo created a public debate that has lead to more telephone calls, emails, letters and faxes to Governor Jon S. Corzine’s office than any other issue since the governor took office.

The Bill was carried by a vote of 5 to 0. It now heads to the Assembly Speaker who may or may not decide to post it for a vote by the full Assembly.

ON LINE SUPPORT

Broadcaster Warren Eckstein from Santa Monica, California, an internationally known pet and animal expert, has been carrying news of Congo’s Bill on his website.

On December 19 Warren wrote that the New Jersey Assembly Agriculture and Natural Resources Committee today released legislation Assembly Deputy Speaker Neil M. Cohen crafted that would immediately change the state’s vicious dog laws.

It was also reported – you will be pleased to hear – from Warren’s website that Congo and his partner Lucia are so happy to be back together.

Elizabeth James on Warren’s website wrote, “I think the appeal could take months but we are optimistic. God willing, New Jersey Assemblyman Neil Cohen’s proposal of Congo’s Law will go through and that will be the first line of defense. We are still receiving mail and email from well wishers and supporters all around the globe! Thank you for all the support and we will keep you posted as we progress.”

On another local website for Asbury Park Press, APP.com for Jersey for comments, blogs and shares, Tom Baldwin of Gannett State Bureau reported Assemblyman Neil Cohen, a professed dog-lover, is quoted as saying under this bill Congo gets saved and the bill gives municipal judges needed latitude to deal with dog-bite cases.

Tom Baldwin continues and I smiled, “The story connects hot-issue circuitry. Mix the gentility of leafy, enlightened Princeton with the dog-lovers and the immigration debate — the landscaper is reported to have been an illegal from Honduras — and the story quickly won global appeal.
“Locally, not since a whale swam up the Delaware River to freshwater Trenton in April 2005 has an animal story grabbed headlines, aside from some reported coyote attacks and New Jersey’s enduring debate over whether to allow hunters shoot black bears.”
And finally Abby K 9 tells us the way to get Congo’s ruling reversed, hopefully, is to contact New Jersey governor Jim Corzine. His office is taking calls (and counting them) to support overturning the death sentence for Congo the German Shepherd.

The governor’s office can be contacted at Office of the Governor, PO Box 001,Trenton, NJ 08625. Calling is preferred, (609-292-6000) but you can also email them through the website.

http://www.nj.gov/cgi-bin/governor/govmail/govmail_1.pl

Choose “Law & Public Safety” on the drop-down menu and on the next page, choose “Pardons & Clemency”. It only takes a few seconds to call – they are interested in the number of callers, not what you have to say – and it does not take much longer to email. Assemblyman Cohen telephone number is (908) 624-0880.

CONGO’S BILL
The following includes a statement from the Bill outlining the relevant details of Congo’s Bill.

On December 17 Senate Bill No. 3019 (A.4597) was introduced for the 212th Legislature. The synopsis said it revises vicious and potentially dangerous dog law; designated Congo’s Law.

The final Statement in the Act concerning vicious and potentially dangerous dogs and designated as Congo’s Law, and amending and supplementing P.L.1989, c.307.
enacted by the Senate and General Assembly of the State of New Jersey said,

“This bill clarifies and revises several provisions of the State law that address vicious and potentially dangerous dogs.  It is designated as Congo’s Law in recognition of Congo, a dog in Princeton, New Jersey, that was declared a vicious dog and subject to an order to be euthanized when, by many accounts, it was protecting its owner and the owner’s family members when a landscaping crew, against the owner’s instructions, came onto the owner’s property.

“Specifically, the bill defines the terms ‘provoked’ and ‘unprovoked.’  Whether a dog is provoked or not is currently the only defense under the law to prevent a dog from being declared vicious when it is acting in defense of itself, its offspring, its owner, or a family member of its owner.  Also, under current law, if a municipal court declares a dog to be vicious, it must be humanely destroyed.  This bill provides the municipal court an alternative to humanely destroying a dog that is declared vicious.

“Under the bill, the court may, for equitable reasons, choose an alternative to destroying the dog if the alternative is sufficient to protect the public and is at least as protective and restrictive as the precautions required for keeping a potentially dangerous dog.  The bill allows for an owner to keep the dog pending disposition of the case and any appeals if the owner agrees to comply with those precautions.  The precautions include posting certain signs on the property and minimizing the dog’s contact and threat to people and other animals in specific ways. 

“In addition, the bill authorizes the court to modify certain requirements for potentially dangerous dogs, and vicious dogs that remain with their owners, to be reasonable, affordable and appropriate to the owner’s circumstances. The bill further provides for visitation by the owner and the owner’s family during any impoundment that is required.

“Furthermore, the bill raises the burden of proof in most cases for finding a dog to be vicious or potentially dangerous to beyond a reasonable doubt, instead of by clear and convincing evidence.  The municipal burden of proof for demonstrating that a dog was not provoked or that the injury was not accidental would be by clear and convincing evidence.  The bill clarifies under the law’s hearing provisions to provide that a hearing on whether the dog is vicious or potentially dangerous will be held unless the owner agrees to relinquish ownership of the dog. 

“The bill further requires the notice to the owner to inform the owner of the potential consequences of not replying to the notice within seven days.  Under current law and the bill, if the owner does not reply within seven days of the notice, or if the owner relinquishes ownership of the dog, the dog may be humanely destroyed.  The bill eliminates the requirement to tattoo a potentially dangerous dog.

“The bill also modifies the provision under current law concerning liability insurance for potentially dangerous dogs.  The bill allows the court to order this insurance for potentially dangerous dogs, and if applicable, vicious dogs, if it is available.  Furthermore, the court is directed to determine a sufficient and reasonable amount of coverage and a reasonable cost for that coverage; and the insurance company is directed to notify the municipality of the coverage and any lapsing of the policy, if the company can lawfully do so.

“Finally, the bill provides additional protections for the public by authorizing municipalities, if a municipality chooses to do so, to establish procedures for recording and investigating complaints about, and requiring appropriate notice to the public concerning, dogs within the jurisdiction of the municipality that are reported to exhibit menacing, threatening, or other aggressive behavior that may lead to injury to a person or a domestic animal, or that have injured a person but have not been the subject of an action pursuant to the State vicious and potentially dangerous dog law.  The municipality must establish these procedures and requirements by ordinance and it is authorized to require an owner of a dog subject to complaints to post signs or take other action determined necessary by the municipality for the protection of the public.

“With Assembly Floor Amendments
(Proposed By Assemblyman Cohen) ADOPTED: DECEMBER 13, 2007
 
These amendments:
      (1) make changes to the definition of “provoked” in the bill;
      (2) remove certain time limitations by which certain actions may be taken in section 2 of the bill; and
      (3) change the municipal burden of proof with respect to whether the dog was not provoked or that the injury was not accidental from beyond a reasonable doubt to by clear and convincing evidence.

Clause 15 states – This act shall take effect immediately, and shall apply to all pending cases and cases in the process of being adjudicated as of the date of enactment of this act, and to any dogs under court order for humane destruction as of January 1, 2007 but which have not been destroyed as of the date of enactment of this act.

The Bill must now go before the Full Assembly.

See Also: http://fmsglobalnews.wordpress.com/2007/12/02/congo-on-doggie-death-row-gets-worldwide-support-and-tv-publicity-for-his-reprieve/

A committee of the New Jersey Senate has considered a new bill called Congo’s Law and there are hopes that Congo, the German Shepherd dog, will no longer be under sentence of death.

Congo was put on “death row” last June as a vicious dog after protecting his mistress, a female dog and three puppies, from an alleged attack with rake by a gardening contractor. When news of his fate reached the Internet animal activists and dog lovers all over the world signed petitions and sent emails to the Judge in Princeton, home of Congo, to save the dog’s life.

This week thanks to a friend, Anne Soden, who lives in Princeton and took part in one of the demonstration to save Congo, I can bring you news that an American Assemblyman called Neil M Cohen from the New Jersey Senate has proposed a Bill to save the life of Congo, the German Shepherd dog sentenced to death. Thanks Anne.

Neil Cohen is quoted as saying,”Congo’s case underscores the need for the state to modernize the law that deals with dog attacks so it is fair for the owners and the animals.”

Congo’s Bill would revise state animal control law provisions that are alleged to be archaic and barbaric, by making it more difficult to label a dog vicious or to put an animal down.

But a USA website (http://abbyK9.blogspot.com) which shows a picture of two of the James children with Congo, adds a cautious note to say, “Please note that Congo being returned to his family is only temporary while the case goes through the appeal. Congo could still be put to sleep for protecting his family. So please, keep contacting the governor’s office to have this matter put to rest once and for all. The calls and emails are helping!” Details of who and where to write or email appear later in this story.

NEW JERSEY SENATE

In December Congo’s Bill, that would immediately change the state’s vicious dog laws, made its first passage through the Senate.

The New Jersey Assemblyman Neil Cohen, who took this action, is an avid defender of the rights of animal and has sponsored several measures to ensure the humane treatment of animals. He has met Congo and his owners, the James family, at their home in Princeton to raise awareness of his legislation and the dog’s potential fate. Neil Cohen says that under current law the only defense for a dog declared vicious is if the dog has been provoked and acted in defense to protect itself, its offspring, its owner or a family member of the owner.

“The nature of a dog is to protect those around them,” said the Assemblyman. “It’s outrageous that Congo may have been provoked into attacking and this fact is being ignored by authorities.”

A lawyer for Congo’s owners has argued that Congo was provoked when the dog mauled a landscaper on June 5 outside a home in Princeton Township. Neil Cohen’s bill (A-4597) will clarify and revise the current vicious dog law to make it more equitable.

The bill would take into consideration provocation by treating a dog provoked to attack differently than an unprovoked dog that caused bodily injury to a person or domestic animal during an attack.

The Assemblyman said the bill would define striking, grabbing, poking and prodding as threatening actions and behaviors that could incite a dog to defend itself, its offspring or its owner or the owner’s family. The legislation would raise the bar for declaring a dog as vicious. It would require a dog to be found vicious beyond a reasonable doubt — the same standard used for humans charged with a crime. The measure also would give municipal courts an alternative to humanely destroying a vicious dog by giving the owner the option to comply with precautions for keeping a potentially dangerous dog.

During the disposition and appeals process, the bill would allow an owner to keep their dog as long as they complied with current law’s precautions for keeping a potentially dangerous dog. Precautions for owners keeping a dog deemed potentially dangerous include posting signs on their property and minimizing a dog’s potential threat to people and other animals. The bill also would allow an owner and owner’s family to visit their dog during times when their dog might be impounded. The bill would establish a three-month statute of limitations for animal control officer to seize and impound alleged vicious or potentially dangerous dogs.

Neil Cohen said the vicious dog law has not been amended since 1994 and it is long overdue for an update. He hoped his legislation would be fast tracked into law to save the life of the Congo.

Congo was ruled vicious by Princeton Township Municipal Judge Russell Annich, Jr., who also ordered that the dog be put down. The judge’s decision has since been stayed and a state Superior Court Judge has allowed the dog to return to his home, pending appeal, with numerous restrictions, including that he is muzzled and kept in a fenced area.

The fate of Congo created a public debate that has lead to more telephone calls, emails, letters and faxes to Governor Jon S. Corzine’s office than any other issue since the governor took office.

The Bill was carried by a vote of 5 to 0. It now heads to the Assembly Speaker who may or may not decide to post it for a vote by the full Assembly.

ON LINE SUPPORT

Broadcaster Warren Eckstein from Santa Monica, California, an internationally known pet and animal expert, has been carrying news of Congo’s Bill on his website.

On December 19 Warren wrote that the New Jersey Assembly Agriculture and Natural Resources Committee today released legislation Assembly Deputy Speaker Neil M. Cohen crafted that would immediately change the state’s vicious dog laws.

It was also reported – you will be pleased to hear – from Warren’s website that Congo and his partner Lucia are so happy to be back together.

Elizabeth James on Warren’s website wrote, “I think the appeal could take months but we are optimistic. God willing, New Jersey Assemblyman Neil Cohen’s proposal of Congo’s Law will go through and that will be the first line of defense. We are still receiving mail and email from well wishers and supporters all around the globe! Thank you for all the support and we will keep you posted as we progress.”

On another local website for Asbury Park Press, APP.com for Jersey for comments, blogs and shares, Tom Baldwin of Gannett State Bureau reported Assemblyman Neil Cohen, a professed dog-lover, is quoted as saying under this bill Congo gets saved and the bill gives municipal judges needed latitude to deal with dog-bite cases.

Tom Baldwin continues and I smiled, “The story connects hot-issue circuitry. Mix the gentility of leafy, enlightened Princeton with the dog-lovers and the immigration debate — the landscaper is reported to have been an illegal from Honduras — and the story quickly won global appeal.
“Locally, not since a whale swam up the Delaware River to freshwater Trenton in April 2005 has an animal story grabbed headlines, aside from some reported coyote attacks and New Jersey’s enduring debate over whether to allow hunters shoot black bears.”
And finally Abby K 9 tells us the way to get Congo’s ruling reversed, hopefully, is to contact New Jersey governor Jim Corzine. His office is taking calls (and counting them) to support overturning the death sentence for Congo the German Shepherd.

The governor’s office can be contacted at Office of the Governor, PO Box 001,Trenton, NJ 08625. Calling is preferred, (609-292-6000) but you can also email them through the website.

http://www.nj.gov/cgi-bin/governor/govmail/govmail_1.pl

Choose “Law & Public Safety” on the drop-down menu and on the next page, choose “Pardons & Clemency”. It only takes a few seconds to call – they are interested in the number of callers, not what you have to say – and it does not take much longer to email. Assemblyman Cohen telephone number is (908) 624-0880.

CONGO’S BILL
The following includes a statement from the Bill outlining the relevant details of Congo’s Bill.

On December 17 Senate Bill No. 3019 (A.4597) was introduced for the 212th Legislature. The synopsis said it revises vicious and potentially dangerous dog law; designated Congo’s Law.

The final Statement in the Act concerning vicious and potentially dangerous dogs and designated as Congo’s Law, and amending and supplementing P.L.1989, c.307.
enacted by the Senate and General Assembly of the State of New Jersey said,

“This bill clarifies and revises several provisions of the State law that address vicious and potentially dangerous dogs.  It is designated as Congo’s Law in recognition of Congo, a dog in Princeton, New Jersey, that was declared a vicious dog and subject to an order to be euthanized when, by many accounts, it was protecting its owner and the owner’s family members when a landscaping crew, against the owner’s instructions, came onto the owner’s property.

“Specifically, the bill defines the terms ‘provoked’ and ‘unprovoked.’  Whether a dog is provoked or not is currently the only defense under the law to prevent a dog from being declared vicious when it is acting in defense of itself, its offspring, its owner, or a family member of its owner.  Also, under current law, if a municipal court declares a dog to be vicious, it must be humanely destroyed.  This bill provides the municipal court an alternative to humanely destroying a dog that is declared vicious.

“Under the bill, the court may, for equitable reasons, choose an alternative to destroying the dog if the alternative is sufficient to protect the public and is at least as protective and restrictive as the precautions required for keeping a potentially dangerous dog.  The bill allows for an owner to keep the dog pending disposition of the case and any appeals if the owner agrees to comply with those precautions.  The precautions include posting certain signs on the property and minimizing the dog’s contact and threat to people and other animals in specific ways. 

“In addition, the bill authorizes the court to modify certain requirements for potentially dangerous dogs, and vicious dogs that remain with their owners, to be reasonable, affordable and appropriate to the owner’s circumstances. The bill further provides for visitation by the owner and the owner’s family during any impoundment that is required.

“Furthermore, the bill raises the burden of proof in most cases for finding a dog to be vicious or potentially dangerous to beyond a reasonable doubt, instead of by clear and convincing evidence.  The municipal burden of proof for demonstrating that a dog was not provoked or that the injury was not accidental would be by clear and convincing evidence.  The bill clarifies under the law’s hearing provisions to provide that a hearing on whether the dog is vicious or potentially dangerous will be held unless the owner agrees to relinquish ownership of the dog. 

“The bill further requires the notice to the owner to inform the owner of the potential consequences of not replying to the notice within seven days.  Under current law and the bill, if the owner does not reply within seven days of the notice, or if the owner relinquishes ownership of the dog, the dog may be humanely destroyed.  The bill eliminates the requirement to tattoo a potentially dangerous dog.

“The bill also modifies the provision under current law concerning liability insurance for potentially dangerous dogs.  The bill allows the court to order this insurance for potentially dangerous dogs, and if applicable, vicious dogs, if it is available.  Furthermore, the court is directed to determine a sufficient and reasonable amount of coverage and a reasonable cost for that coverage; and the insurance company is directed to notify the municipality of the coverage and any lapsing of the policy, if the company can lawfully do so.

“Finally, the bill provides additional protections for the public by authorizing municipalities, if a municipality chooses to do so, to establish procedures for recording and investigating complaints about, and requiring appropriate notice to the public concerning, dogs within the jurisdiction of the municipality that are reported to exhibit menacing, threatening, or other aggressive behavior that may lead to injury to a person or a domestic animal, or that have injured a person but have not been the subject of an action pursuant to the State vicious and potentially dangerous dog law.  The municipality must establish these procedures and requirements by ordinance and it is authorized to require an owner of a dog subject to complaints to post signs or take other action determined necessary by the municipality for the protection of the public.

“With Assembly Floor Amendments
(Proposed By Assemblyman Cohen) ADOPTED: DECEMBER 13, 2007
 
These amendments:
      (1) make changes to the definition of “provoked” in the bill;
      (2) remove certain time limitations by which certain actions may be taken in section 2 of the bill; and
      (3) change the municipal burden of proof with respect to whether the dog was not provoked or that the injury was not accidental from beyond a reasonable doubt to by clear and convincing evidence.

Clause 15 states – This act shall take effect immediately, and shall apply to all pending cases and cases in the process of being adjudicated as of the date of enactment of this act, and to any dogs under court order for humane destruction as of January 1, 2007 but which have not been destroyed as of the date of enactment of this act.

The Bill must now go before the Full Assembly.

by Jeanne Hambleton  © 2008
NFA Leader Against Pain-Advocate  

A committee of the New Jersey Senate has considered a new bill called Congo’s Law and there are hopes that Congo, the German Shepherd dog, will no longer be under sentence of death.

Congo was put on “death row” last June as a vicious dog after protecting his mistress, a female dog and three puppies, from an alleged attack with rake by a gardening contractor. When news of his fate reached the Internet animal activists and dog lovers all over the world signed petitions and sent emails to the Judge in Princeton, home of Congo, to save the dog’s life.

This week thanks to a friend, Anne Soden, who lives in Princeton and took part in one of the demonstration to save Congo, I can bring you news that an American Assemblyman called Neil M Cohen from the New Jersey Senate has proposed a Bill to save the life of Congo, the German Shepherd dog sentenced to death. Thanks Anne.

Neil Cohen is quoted as saying,”Congo’s case underscores the need for the state to modernize the law that deals with dog attacks so it is fair for the owners and the animals.”

Congo’s Bill would revise state animal control law provisions that are alleged to be archaic and barbaric, by making it more difficult to label a dog vicious or to put an animal down.

But a USA website (http://abbyK9.blogspot.com) which shows a picture of two of the James children with Congo, adds a cautious note to say, “Please note that Congo being returned to his family is only temporary while the case goes through the appeal. Congo could still be put to sleep for protecting his family. So please, keep contacting the governor’s office to have this matter put to rest once and for all. The calls and emails are helping!” Details of who and where to write or email appear later in this story.

NEW JERSEY SENATE

In December Congo’s Bill, that would immediately change the state’s vicious dog laws, made its first passage through the Senate.

The New Jersey Assemblyman Neil Cohen, who took this action, is an avid defender of the rights of animal and has sponsored several measures to ensure the humane treatment of animals. He has met Congo and his owners, the James family, at their home in Princeton to raise awareness of his legislation and the dog’s potential fate. Neil Cohen says that under current law the only defense for a dog declared vicious is if the dog has been provoked and acted in defense to protect itself, its offspring, its owner or a family member of the owner.

“The nature of a dog is to protect those around them,” said the Assemblyman. “It’s outrageous that Congo may have been provoked into attacking and this fact is being ignored by authorities.”

A lawyer for Congo’s owners has argued that Congo was provoked when the dog mauled a landscaper on June 5 outside a home in Princeton Township. Neil Cohen’s bill (A-4597) will clarify and revise the current vicious dog law to make it more equitable.

The bill would take into consideration provocation by treating a dog provoked to attack differently than an unprovoked dog that caused bodily injury to a person or domestic animal during an attack.

The Assemblyman said the bill would define striking, grabbing, poking and prodding as threatening actions and behaviors that could incite a dog to defend itself, its offspring or its owner or the owner’s family. The legislation would raise the bar for declaring a dog as vicious. It would require a dog to be found vicious beyond a reasonable doubt — the same standard used for humans charged with a crime. The measure also would give municipal courts an alternative to humanely destroying a vicious dog by giving the owner the option to comply with precautions for keeping a potentially dangerous dog.

During the disposition and appeals process, the bill would allow an owner to keep their dog as long as they complied with current law’s precautions for keeping a potentially dangerous dog. Precautions for owners keeping a dog deemed potentially dangerous include posting signs on their property and minimizing a dog’s potential threat to people and other animals. The bill also would allow an owner and owner’s family to visit their dog during times when their dog might be impounded. The bill would establish a three-month statute of limitations for animal control officer to
seize and impound alleged vicious or potentially dangerous dogs.

Neil Cohen said the vicious dog law has not been amended since 1994 and it is long overdue for an update. He hoped his legislation would be fast tracked into law to save the life of the Congo.

Congo was ruled vicious by Princeton Township Municipal Judge Russell Annich, Jr., who also ordered that the dog be put down. The judge’s decision has since been stayed and a state Superior Court Judge has allowed the dog to return to his home, pending appeal, with numerous restrictions, including that he is muzzled and kept in a fenced area.

The fate of Congo created a public debate that has lead to more telephone calls, emails, letters and faxes to Governor Jon S. Corzine’s office than any other issue since the governor took office.

The Bill was carried by a vote of 5 to 0. It now heads to the Assembly Speaker who may or may not decide to post it for a vote by the full Assembly.

ON LINE SUPPORT

Broadcaster Warren Eckstein from Santa Monica, California, an internationally known pet and animal expert, has been carrying news of Congo’s Bill on his website.

(http://wareneckstein.com)

On December 19 Warren wrote that the New Jersey Assembly Agriculture and Natural Resources Committee today released legislation Assembly Deputy Speaker Neil M. Cohen crafted that would immediately change the state’s vicious dog laws.

It was also reported – you will be pleased to hear – from Warren’s website that Congo and his partner Lucia are so happy to be back together.

Elizabeth James on Warren’s website wrote, “I think the appeal could take months but we are optimistic. God willing, New Jersey Assemblyman Neil Cohen’s proposal of Congo’s Law will go through and that will be the first line of defense. We are still receiving mail and email from well wishers and supporters all around the globe! Thank you for all the support and we will keep you posted as we progress.”

On another local website for Asbury Park Press, APP.com for Jersey for comments, blogs and shares, Tom Baldwin of Gannett State Bureau reported Assemblyman Neil Cohen, a professed dog-lover, is quoted as saying under this bill Congo gets saved and the bill gives municipal judges needed latitude to deal with dog-bite cases.

Tom Baldwin continues and I smiled, “The story connects hot-issue circuitry. Mix the gentility of leafy, enlightened Princeton with the dog-lovers and the immigration debate — the landscaper is reported to have been an illegal from Honduras — and the story quickly won global appeal.
“Locally, not since a whale swam up the Delaware River to freshwater Trenton in April 2005 has an animal story grabbed headlines, aside from some reported coyote attacks and New Jersey’s enduring debate over whether to allow hunters shoot black bears.”
And finally Abby K 9 tells us the way to get Congo’s ruling reversed, hopefully, is to contact New Jersey governor Jim Corzine. His office is taking calls (and counting them) to support overturning the death sentence for Congo the German Shepherd.

The governor’s office can be contacted at Office of the Governor, PO Box 001,Trenton, NJ 08625. Calling is preferred, (609-292-6000) but you can also email them through the website.

http://www.nj.gov/cgi-bin/governor/govmail/govmail_1.pl

Choose “Law & Public Safety” on the drop-down menu and on the next page, choose “Pardons & Clemency”. It only takes a few seconds to call – they are interested in the number of callers, not what you have to say – and it does not take much longer to email. Assemblyman Cohen telephone number is (908) 624-0880.

CONGO’S BILL
The following includes a statement from the Bill outlining the relevant details of Congo’s Bill.

On December 17 Senate Bill No. 3019 (A.4597) was introduced for the 212th Legislature. The synopsis said it revises vicious and potentially dangerous dog law; designated Congo’s Law.

The final Statement in the Act concerning vicious and potentially dangerous dogs and designated as Congo’s Law, and amending and supplementing P.L.1989, c.307.
enacted by the Senate and General Assembly of the State of New Jersey said,

“This bill clarifies and revises several provisions of the State law that address vicious and potentially dangerous dogs.  It is designated as Congo’s Law in recognition of Congo, a dog in Princeton, New Jersey, that was declared a vicious dog and subject to an order to be euthanized when, by many accounts, it was protecting its owner and the owner’s family members when a landscaping crew, against the owner’s instructions, came onto the owner’s property.

“Specifically, the bill defines the terms ‘provoked’ and ‘unprovoked.’  Whether a dog is provoked or not is currently the only defense under the law to prevent a dog from being declared vicious when it is acting in defense of itself, its offspring, its owner, or a family member of its owner.  Also, under current law, if a municipal court declares a dog to be vicious, it must be humanely destroyed.  This bill provides the municipal court an alternative to humanely destroying a dog that is declared vicious.

“Under the bill, the court may, for equitable reasons, choose an alternative to destroying the dog if the alternative is sufficient to protect the public and is at least as protective and restrictive as the precautions required for keeping a potentially dangerous dog.  The bill allows for an owner to keep the dog pending disposition of the case and any appeals if the owner agrees to comply with those precautions.  The precautions include posting certain signs on the property and minimizing the dog’s contact and threat to people and other animals in specific ways. 

“In addition, the bill authorizes the court to modify certain requirements for potentially dangerous dogs, and vicious dogs that remain with their owners, to be reasonable, affordable and appropriate to the owner’s circumstances. The bill further provides for visitation by the owner and the owner’s family during any impoundment that is required.

“Furthermore, the bill raises the burden of proof in most cases for finding a dog to be vicious or potentially dangerous to beyond a reasonable doubt, instead of by clear and convincing evidence.  The municipal burden of proof for demonstrating that a dog was not provoked or that the injury was not accidental would be by clear and convincing evidence.  The bill clarifies under the law’s hearing provisions to provide that a hearing on whether the dog is vicious or potentially dangerous will be held unless the owner agrees to relinquish ownership of the dog. 

“The bill further requires the notice to the owner to inform the owner of the potential consequences of not replying to the notice within seven days.  Under current law and the bill, if the owner does not reply within seven days of the notice, or if the owner relinquishes ownership of the dog, the dog may be humanely destroyed.  The bill eliminates the requirement to tattoo a potentially dangerous dog.

“The bill also modifies the provision under current law concerning liability insurance for potentially dangerous dogs.  The bill allows the court to order this insurance for potentially dangerous dogs, and if applicable, vicious dogs, if it is available.  Furthermore, the court is directed to determine a sufficient and reasonable amount of coverage and a reasonable cost for that coverage; and the insurance company is directed to notify the municipality of the coverage and any lapsing of the policy, if the company can lawfully do so.

“Finally, the bill provides additional protections for the public by authorizing municipalities, if a municipality chooses to do so, to establish procedures for recording and investigating complaints about, and requiring appropriate notice to the public concerning, dogs within the jurisdiction of the municipality that are reported to exhibit menacing, threatening, or other aggressive behavior that may lead to injury to a person or a domestic animal, or that have injured a person but have not been the subject of an action pursuant to the State vicious and potentially dangerous dog law.  The municipality must establish these procedures and requirements by ordinance and it is authorized to require an owner of a dog subject to complaints to post signs or take other action determined necessary by the municipality for the protection of the public.

“With Assembly Floor Amendments
(Proposed By Assemblyman Cohen) ADOPTED: DECEMBER 13, 2007
 
These amendments:
      (1) make changes to the definition of “provoked” in the bill;
      (2) remove certain time limitations by which certain actions may be taken in section 2 of the bill; and
      (3) change the municipal burden of proof with respect to whether the dog was not provoked or that the injury was not accidental from beyond a reasonable doubt to by clear and convincing evidence.

Clause 15 states – This act shall take effect immediately, and shall apply to all pending cases and cases in the process of being adjudicated as of the date of enactment of this act, and to any dogs under court order for humane destruction as of January 1, 2007 but which have not been destroyed as of the date of enactment of this act.

The Bill must now go before the Full Assembly.

See Also: http://www.ipetitions.com/petition/savecongo/

MAKING MEMORIES AND SOBERING THOUGHTS FOR FIBROMITES

by Jeanne Hambleton © 2007
NFA Leader Against Pain-Advocate
 
I well remember how much I enjoyed Gene Kelly’s performance in the film “Singing in the Rain”. It made me feel so good, in spite of the bad weather, and between us, I really felt like being silly, running outside in the rain and singing my head off. But as my dear late Dad would have said, “Here’s a penny. Go in the next street!” That does not say much for my voice but the thought was there.

It is odd but these days you seldom hear children singing while playing. Do they still teach singing in school – all those pomp and circumstance songs like ‘Jerusalem’, ‘Land of Hope and Glory’ to name but two? Most children seem to know, ‘You’ll never walk alone’, but I guess that is down to the football fans. I seem to think we were encouraged to sing to get some fresh air in our lungs. I even remember doing breathing exercises at school – that must have been when Adam was a lad!

It also seems as if most children do not want to play in the rain and hate to get wet. What happy childhood memories come back when you see a picture of a young child in a hooded raincoat with wellies splashing in big puddles and giggling? I would think Health & Safety and the PC (Politically Correct) Brigade would have something to say about that these days – too dangerous – the child will slip over and hurt itself.

All this talk about singing and dancing in the rain brings me nicely to a little story, which I hope you will enjoy. To be truthful I am hoping to start an epidemic of people singing and dancing in the rain and getting them washed while they are at it. We could change the words, “I’m singing and washing in the rain”. Read on and you will understand where I am coming from. Regrettably I cannot remember which fibromite sent it to me – fibro fog – but thanks.
 
IT’S RAINING

A little girl had been shopping with her Mom in Zellers. She must have been 6 years old, this beautiful red haired, freckle faced image of innocence. It was pouring with rain outside the store. It was the kind of rain that gushes over the top of rain gutters, so much in a hurry to hit the earth it has no time to flow down the spout. We all stood there under the awning and just outside the door of Zellers.

We waited, some patiently, others irritated because it messed up their hurried day.  I am always mesmerized by rainfall.  I got lost in the sound and sight of the heavens washing away the dirt and dust of the world. Memories of running, splashing so carefree as a child came pouring in as a welcome reprieve from the worries of my day.

The little voice was so sweet as it broke the hypnotic trance we were all caught in.
“Mom, let’s run through the rain,” she said.

 ”What?” Mom asked.

“Lets run through the rain!” she repeated.

“No, Honey. We’ll wait until it slows down a bit,” Mom replied.

This young child waited about another minute and repeated: “Mom, let’s run through the rain,”

“We’ll get soaked if we do,” Mom said.

“No, we won’t, Mom.  That’s not what you said this morning,” the young girl said as she tugged at her Mom’s arm.

“This morning?  When did I say we could run through the rain and not get wet?”

“Don’t you remember?  When you were talking to Daddy about his cancer, you said, ‘If God can get us through this, He can get us through anything!’”

The entire crowd stopped dead silent.  I swear you couldn’t hear anything but the rain.  We all stood silently.  No one came or left in the next few moments.

 Mom paused and thought for a moment about what she would say.  Now some would laugh it off and scold the child for being silly.  Some might even ignore what was said.  But this was a moment of affirmation in a young child’s life:  a time when innocent trust can be nurtured so that it will bloom into faith.

“Honey, you are absolutely right.  Let’s run through the rain.  If GOD lets us get wet, well maybe we just needed washing,” Mom said.

Then off they ran.  We all stood watching, smiling and laughing as they darted past the cars and, yes, through the puddles.  They held their shopping bags over their heads just in case.  They got soaked.  But they were followed by a few who screamed and laughed like children all the way to their cars.

And, yes, I did.  I ran.  I got wet.  I needed washing.

Circumstances or people can take away your material possessions.  They can take away your money, and they can also take away your health.  But no one can ever take away your precious memories.  So, don’t forget to make time and take the opportunities to make memories everyday.

“To everything there is a season, and a time to every purpose under the heaven.” Ecclesiastes 3:1

I hope you still take the time to run through the rain. They say it takes a minute to find a special person, an hour to appreciate them, a day to love them, but then an entire life to forget them. Share this story with the people you’ll never forget.  It’s a short message and it will let them know that you’ll never forget them.

If you don’t tell anyone, it means you’re in a hurry.  A pity! Take the time to live!!!

Keep in touch with your friends.  You never know when you’ll need each other or you no longer can keep in touch – and don’t forget to run in the rain!

FMS Global News

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Tenderpoints Newsletter

SOUNDING OFF ABOUT FIBROMYALGIA AWARENESS WEEK

By Jeanne Hambleton© UK Fibromite

I know I am always going on about raising awareness and fibromyalgia and this is especially important as far as the UK Government is concerned. Although we have E Petitions allegedly for the eyes of the Prime Minister, asking for support for various aspects of fibromyalgia, I have my doubts as to whether these will actually achieved any funding for research or recognition for FM – oh me of little faith.

Two of the 4 E Petitions about fibromyalgia on the No.10 Downing Street website will end this month (August) and as a supporter I am hoping to receive comments from the No.10 Downing Street web team (almost certainly not the Prime Minister). I feel sure the Prime Minister does not have time to read all the E Petitions – too busy with his politics. I almost have the impression the E Petitions were designed to save the postman delivering hundred and hundreds of letters which someone has to open and read, although rumour has it the idea of E Petitions was thought to be a bad idea.

As a matter of interest my new E Petition is to help replace those that are about to expire and can be found at the following website. It only takes a minute to do and you will feel go you have supported us. PLEASE would you please sign? I need 1000 signatures before it will be considered – 2000 would be nice. Tell your friends and family PLEASE. I am not on commission!

http://petitions.pm.gov.uk/FIBROFUNDING/

But my reason for writing is other ways to raising awareness during Fibromyalgia Awareness Week.

For us here in the UK and possibly the world over, the 8th to 15th September is Fibromyalgia Awareness Week. We do still of course have another annual event on 12th May – World Fibromyalgia Awareness Day. If you did nothing on that day to further the cause, now is your big chance.

Yes you have guessed it. I am going to talk about doing your bit for this FM Week. Raising funds would be a plus but raising awareness is far more important. Not sure about you, but I am pig sick of people looking at me and saying, “Fibro what?” If you listen carefully you can hear them thinking, “Poor girl – I wonder how long she has to live?”

If you are going to dismiss that thought be sure to tell them, we may not die from FM but as sure as eggs are eggs we will live with the pain for the rest of our lives or until someone finds a cure. (That is why you are signing the E Petition!)

What can you do? I have made several suggestions below with varying amounts of effort, so no excuses please.

NOT TOO HARD WITH FAMILY HELP
Find everything you have in your home that refers to fibromyalgia and invite your friends and neighbours to a need-to-know coffee morning, or afternoon tea and cake (if you don’t do mornings!) You can talk about each item connected with FM, or ask how the last 10 years has been for each of your visitors. When it is your turn you can recall what you used to do and how disabled you are now. Remind them it is an invisible disability and although you look so well you feel so awful.
Keep it bright and light with a few funny fibro stories. This event could even provide you with a few fit helpers for the future if you stage a fund raising event for FM to help your local Support Group.

ARMCHAIR EFFORT
If life is a struggle and a coffee morning is all too much, you could start your own letter writing campaign. Here in the UK you could write to your MP or in the States try your Senator? The MP’s address will be in your local telephone book. If you cannot find it ring the local paper. If you are feeling inspired you could write to the Prime Minister himself – Gordon Brown PM, 10, Downing Street, London, SW1A2AA, or email his assistant james.bowler@hm-treasury.gsi.gov.uk. David Cameron can be reached at camerond@parliament.uk. I am guessing here but I would think that Sir Menzies Campbell could be reached using campbellm@parliament.uk

The mail address of most MPs is their surname followed by the initial and the address – for example the Health Minister Alan Johnson MP – his address is johnsona@parliament.uk.

If you are using snail mail send your letter to your MP at House of Commons, London, SW1A 0AA

For information about websites, biographies and email addresses search for your MP in alphabetical order at http://www.parliament.uk/directories/directories.cfm

If you do not know who your MP is try http://www.theyworkforyou.com/ and type on your postcode. This will produce a message box, so have our message ready to cut and pate into the box.

If you think you have written a good letter to the PM, the Health Minister and your MP about your FM appealing for Government support for research to find a cure, and speed up diagnosis, including details of your life as a person with an invisible disability – the symptoms – pain 24/7, chronic fatigue, sleeplessness, cognitive problems, IBS, RLS and all the other nasties – send a copy to the Editor of your local paper. Ask him to print it with the readers’ letters, adding your own comments about what you hope the PM will agree. It is a good idea to use bullet points for the symptoms (easier to read).

Now you are on roll! Why not send a copy to your local radio station and the regional TV station? You never know they just might wonder – like everyone else – exactly what fibromyalgia means.

GOING OUT TO THE PUBLIC
If you access to lots of fibromyalgia literature you could ask your local superstore manager if you can stand near the entrance one busy afternoon and hand out literature. If you have friends you could have a table and chairs with fibromites who can talk about the syndrome and maybe encourage anyone interested to join the Group.

EDUCATING STUDENT DOCTORS
By now you should be full of confidence and really ready to go anywhere to tell your story. Contact you local PCT – Primary Care Trust (details in your local telephone book) – who are responsible for the hospitals and doctors in your area. Ask if you could talk to a class of student doctors about fibromyalgia from a patient’s perspective? You could answer their questions and help them become more knowledgeable about diagnosing FM for future patients. You would indeed be raising awareness by doing this, as so many GPs believe it is all in our head. The Fibromyalgia Association of the UK, http://www.fibromyalgia-associationuk.org, has prepared literature for the medical profession. I believe the American NFA – http://www.fmaware.org – also had medical literature for doctors.

Yes we now believe it is all in our head – but not as the GP suggests. Does your GP think it is in your imagination and that you are a mad malingerer? If so tell him it is now said that FM is due to a chemical imbalance in the brain.

My final thought would be to festoon your house or garden with balloons with a sign in the window saying “Happy Anniversary Fibromyalgia”. Someone is bound to ask you who is Fibromyalgia. Take a photograph and send it to the local paper with a caption saying you are celebration Fibromyalgia Awareness Week. I feel sure you will find this an uplifting experience and enjoy the fun. At the end of all this raising awareness you will feel you have achieved something by spreading the word – which as we know is FIBROMYALGIA.

Do write and tell me about your achievements – we can then have another go at more publicity for FM.

FMS Global News

Tenderpoints

Global Health Vision

Characteristics and healthcare costs of patients with fibromyalgia syndrome.

Berger A, Dukes E, Martin S, Edelsberg J, Oster G.
Policy Analysis, Inc. (PAI), Brookline, MA, USA.

Purpose: To examine the characteristics and healthcare costs of fibromyalgia syndrome (FMS) patients in clinical practice. Materials and methods: Using a US health-insurance database, we identified all patients, aged >/= 18 years, with any healthcare encounters for FMS (ICD-9-CM diagnosis code 729.1) in each year of the 3-year period, 1 July 2002 to 30 June 2005. A comparison group was then constituted, consisting of randomly selected patients without any healthcare encounters for FMS during this 3-year period. Comparison group patients were matched to FMS patients based on age and sex. Characteristics and healthcare costs of FMS patients and comparison group patients were then examined over the 1-year period, 1 July 2004 to 30 June 2005 (the most recent year for which data were available at the time of the study). Results: The study sample consisted of 33,176 FMS patients and an identical number in the comparison group. Mean age was 46 years, and 75% were women. FMS patients were more likely to have various comorbidities, including painful neuropathies (23% vs. 3% for comparison group), anxiety (5% vs. 1%), and depression (12% vs. 3%) (all p < 0.001); they also were more likely to have used pain-related pharmacotherapy (65% vs. 34% for comparison group; p < 0.001). Mean (SD) total healthcare costs over 12 months were about three times higher among FMS patients [$9573 ($20,135) vs. $3291 ($13,643); p < 0.001]; median costs were fivefold higher ($4247 vs. $822; p < 0.001). Conclusions: Patients with FMS have comparatively high levels of comorbidities and high levels of healthcare utilization and cost.

PMID: 17655684 [PubMed - as supplied by publisher]

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Mouse genome will help identify causes of environmental disease

Research on the DNA of 15 mouse strains commonly used in biomedical studies is expected to help scientists determine the genes related to susceptibility to environmental disease. The body of data is now publicly available in a catalog of genetic variants, which displays the data as a mouse haplotype map, a tool that separates chromosomes in to many small segments, helping researchers find genes and genetic variations in mice that may affect health and disease. The haplotype map appearing online in the July 29th issue of Nature is the first published full descriptive analysis of the “Mouse Genome Resequencing and SNP Discovery Project” conducted by the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health.

“These data allow researchers to compare the genetic makeup of one mouse strain to another, and perform the necessary genetic analyses to determine why some individuals might be more susceptible to disease than another. This puts us one step closer to understanding individual susceptibility to environmental toxins in humans. We also hope that pharmaceutical companies developing new treatments for environmental diseases will find these data and this paper as a valuable resource,” said David A. Schwartz. M.D., NIEHS Director.

The paper describes in detail the laborious and technology-driven approaches that were used to identify 8.27 million high quality SNPs distributed among the genomes of 15 mouse strains. Single Nucleotide Polymorphisms, or SNPs (known as snips), are single genetic changes, or variations, that can occur in a DNA sequence.

Much of the project was conducted through a contract between the National Toxicology Program at NIEHS and Perlegen Sciences, Inc. of Mountain View Calif.

“The database of mouse genetic variation should facilitate a wide range of important biological studies, and helps demonstrate the utility of this array technology approach,” said David R. Cox, M.D., Ph.D., chief scientific officer at Perlegen Sciences, Inc.

The Perlegen scientists used C57BL/6J the first mouse strain to undergo DNA sequencing as their standard reference to conduct the re-sequencing on the four wild-derived and eleven classical mouse strains. The technology used, the oligonucleotide array, was also used to discover common DNA variation in the human genome.

The arrays looked at about 1.49 billion bases (58 percent) of the 2.57 billion base pair of their standard reference strain. The data were then used to develop the haplotype map which contains 40,898 segments.

“The data will be a valuable resource to many, including the National Toxicology Program,” Schwartz says. The National Toxicology Program (NTP) is an interagency program, headquartered at NIEHS, with the mission to coordinate, conduct and communicate toxicological research across the U.S. government.

“The NTP is looking forward to exploring the responses of these strains of mice to various environmental agents,” said John Bucher, Ph.D., the new associate director of the NTP.

Frank M. Johnson, Ph. D., an NTP research geneticist and one of the authors of the Nature paper, adds that systematically characterizing even more mouse strains for susceptibility to toxins will not only help with genetic analysis, but better position researchers to do intervention studies.

###
The data are publicly available on the National Center for Biotechnology Information Web site at http://www.ncbi.nlm.nih.gov/SNP/ and at a Web site developed by Perlegen at http://mouse.perlegen.com which allows researchers to download SNPs, genotypes, and LR-PCR primer pairs, which are currently mapped to NCBI Build 36.

In addition to the NTP and Perlegen Sciences scientists, other key collaborators on the project include researchers from the Department of Computer Science and Department of Human Genetics, University of California, Los Angeles; the Department of Computer Science and Engineering, University of California, San Diego; The Jackson Laboratory, Bar Harbor, Maine; Broad Institute of Harvard and MIT; and the Center for Human Genetic Research, Massachusetts General Hospital.

Reference: Kelly A. Frazer, Eleazar Eskin, Hyun Min Kang, Molly A. Bogue, David A. Hinds, Erica J. Beilharz, Robert V. Gupta, Julie Montgomery, Matt M. Morenzoni, Geoffrey B. Nilsen, Charit L. Pethiyagoda, Laura L. Stuve, Frank M. Johnson, Mark J. Daly, Claire M. Wade, David R. Cox. A sequence-based variation map of 8.27 million SNPs in inbred mouse strains. Nature, 2007

The National Institute of Environmental Health Sciences (NIEHS), a component of the National Institutes of Health, supports research to understand the effects of the environment on human health. For more information on environmental health topics, please visit our website at http://www.niehs.nih.gov/.

The National Institutes of Health (NIH) — The Nation’s Medical Research Agency — includes 27 Institutes and Centers and is a component of the U. S. Department of Health and Human Services. It is the primary federal agency for conducting and supporting basic, clinical, and translational medical research, and it investigates the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit http://www.nih.gov.

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Increased Levels of Neurotrophins Are Not Specific for Chronic Migraine: Evidence from Primary Fibromyalgia Syndrome.

Sarchielli P, Mancini ML, Floridi A, Coppola F, Rossi C, Nardi K, Acciarresi M, Alberto Pini L, Calabresi P.

Neurologic Clinic, Department of Medical and Surgical Specialties and Public Health, University of Perugia, Perugia, Italy.

All data obtained in experimental animal pain models support the role of nerve growth factor (NGF) as a putative candidate intervening in the pathogenesis of chronic pain, including chronic daily headache (CDH). Few studies have been carried out to establish its role in maintaining pain states in humans. The present study was aimed at investigating cerebrospinal fluid (CSF) levels of NGF and brain-derived neurotrophic factor (BDNF), both measured by sensitive immunoassay, in 20 chronic migraine (CM) patients and 20 patients affected by primary fibromyalgia syndrome (PFMS), compared with those of 20 age-matched control subjects. Significantly higher levels of both neurotrophins and glutamate were found. A significantly positive correlation emerged between CSF values of BDNF and those of NGF (See Note) in CM and PFMS patients, respectively. These findings suggest the possibility of a NGF-mediated up-regulation of BDNF involved in the pathophysiological events underlying long-term neuroplastic changes in persistent chronic painful conditions, such as CM and fibromyalgia. NGF might indirectly exert its effect through enhancing glutamatergic transmission via BDNF. The above mechanisms could account for sustained central sensitization in both chronic pain states. PERSPECTIVE: This article presents findings of higher NGF and BDNF levels correlated to increased glutamate levels in the CSF of both chronic migraine and fibromyalgia patients. This opens new insights into the pathogenic mechanisms of chronic pain and offers clinicians new therapeutic perspectives targeting the above mechanisms in both painful disorders.

PMID: 17611164 [PubMed - as supplied by publisher]

1: J Pain. 2007 Jul 3; [Epub ahead of print]

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